Israeli airstrikes on Tehran continued overnight into Wednesday, intensifying a six-day confrontation with the Islamic Republic. In response, Iran has issued a direct warning to the United States, stating that any American military involvement would cause “irreparable damage”.
The warning was delivered by Iran’s Supreme Leader, Ayatollah Ali Khamenei, whose statement was read aloud by a state television presenter. The broadcast showed a static image of the 86-year-old cleric rather than a live or recorded video, raising questions about his location and personal security. State television indicated a full video recording would be released later.
“Any military participation by the United States in this matter will undoubtedly result in irreparable damage to them,” the statement read. Khamenei also urged Iranian officials to “continue their work with strength and faith in God”, adding, “God will certainly and undoubtedly lead the Iranian people to victory.”
This is Khamenei’s second public message since Israeli strikes began on Friday. The decision not to appear in person has fuelled speculation about the cleric’s whereabouts, which remain unknown amid an intensifying military campaign targeting key infrastructure and security sites in and around Tehran.
US Reaction and Strategic Movements
US President Donald Trump responded to the Iranian warning on Tuesday with a series of remarks on social media, demanding Iran’s “unconditional surrender” and addressing Khamenei directly. Trump claimed US intelligence services were aware of Khamenei’s location but stated that there were no current plans to target him “at least not for now”.
At the same time, international media outlets have reported unusual levels of US aerial activity in the wider Middle East region. Though the US military has not confirmed any new deployments, increased surveillance and positioning of air assets have been observed, suggesting that contingency plans are in motion.
Civilian and Military Casualties Mount in Iran
Human Rights Activists in Iran (HRAI), a monitoring organisation that gained prominence during the 2022 anti-government protests, has reported mounting casualties as Israeli airstrikes intensify. According to its latest figures, at least 239 civilians and 126 members of Iran’s security forces have been killed since the conflict began. The data is based on cross-referenced reports from local informants and sources inside Iran.
Israeli Domestic Response
In Israel, the government has begun easing civilian restrictions introduced at the onset of the conflict. Defence Minister Israel Katz announced that, although schools remain closed, many workplaces are now allowed to reopen, especially in areas less frequently targeted by missile attacks.
“This decision to gradually open the economy in the various regions is a message of victory over the Iranian enemy,” Katz said. He added that a reduction in the frequency and scale of Iranian attacks has allowed Israeli defence systems to operate with increased precision.
International Diplomatic Efforts
The European Union is expected to convene an emergency Foreign Affairs Council session to address the crisis, though a unified statement has yet to be issued. Russia and China have both called for restraint and warned against further escalation. Meanwhile, the United Nations Security Council is due to meet later in the week.
Despite growing international concern, neither side has indicated a willingness to engage in ceasefire negotiations. The risk of a broader regional war remains high, particularly in light of Iran’s explicit warnings to the United States and the observable increase in US military activity.
Read also:
Iran Links Israeli Strikes to US Policy, Casts Doubt on Oman Negotiations

